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1.
Rev. chil. obstet. ginecol ; 77(6): 453-456, 2012. ilus
Article in Spanish | LILACS | ID: lil-665595

ABSTRACT

Se presenta el caso de una paciente que consultó por metrorragia posmenopaúsica. En la biopsia histeroscópica dirigida se informó de adenocarcinoma de endometrio endometrioide bien diferenciado. Se practicó histerectomía, doble anexectomía y lavados peritoneales. Durante el acto quirúrgico se valoró el grado de infiltración miometrial, que al revelar afectación del útero hasta la serosa, implicó la realización de linfadenectomía de espacios pélvicos y paraaórtico. El diagnóstico definitivo anatomopatológico fue de adenocarcinoma de endometrio tipo endometrioide de patrón sertoliforme moderadamente diferenciado. El estadío FIGO fue IIIA, por lo que se indicó quimioterapia y radioterapia como tratamiento adyuvante. A los 2 años la paciente presenta recidiva ganglionar y metástasis pulmonares con progresión a pesar del tratamiento quimioterápico, por lo que finalmente fallece.


We report a case of a patient with postmenopausal bleeding. In hysteroscopic directed biopsy was reported endometrioid endometrial adenocarcinoma well differentiated, so that she underwent total hysterectomy, both salpingo-oophorectomy and peritoneal washings. In the surgery, we evaluated the miometrial infiltration, with report invasion until serosa, so we practised pelvic and paraaortic lymphadenectomy. The pathologic diagnosis was sertoliform endometrioid carcinoma of the endometrium with moderate differentiation. The FIGO stage was IIIA, and we indicated chemotherapy and radiotherapy. Two year after, the patient presented nodal recurrence and lung metastases with no response to the chemotherapy drugs, so she dies.


Subject(s)
Humans , Female , Middle Aged , Adenocarcinoma/diagnosis , Adenocarcinoma/pathology , Sertoli Cells/pathology , Endometrial Neoplasms/diagnosis , Endometrial Neoplasms/pathology , Adenocarcinoma/surgery , Fatal Outcome , Hysterectomy , Metrorrhagia/etiology , Endometrial Neoplasms/surgery , Postmenopause , Sertoli Cell Tumor/surgery
2.
Rev. chil. obstet. ginecol ; 76(6): 420-426, 2011. ilus
Article in Spanish | LILACS | ID: lil-612142

ABSTRACT

Los tumores müllerianos mixtos malignos o carcinosarcomas son neoplasias poco frecuentes y altamente agresivas que suelen presentarse en pacientes mayores de 60 años, generalmente en forma de metrorragia posmenopáusica y/o presencia de masas uterinas. Entre los factores de riesgo reconocidos está descrita la historia de irradiación previa del área pélvica. Presentamos 3 casos clínicos de pacientes diagnosticadas y tratadas de tumores müllerianos mixtos uterinos malignos, existiendo en todos ellos el antecedente de neoplasias que habían precisado radioterapia pélvica como parte de su tratamiento.


The malignant Mullerian mixed tumors are rare and highly aggressive, these tumors usually occur in women over 60 years and the most common clinical appearance is that of postmenopausal vaginal bleeding or the presence of uterine mass. As a risk factor is described the history of prior irradiation of the pelvic area. We reported the case of three patients with mullerian mixed tumors, in all these cases the patients have a history of cancer who required pelvic radiation as part of their treatment.


Subject(s)
Humans , Female , Aged , Aged, 80 and over , Uterine Neoplasms/surgery , Uterine Neoplasms/diagnosis , Radiotherapy, Adjuvant/adverse effects , Mixed Tumor, Mullerian/surgery , Mixed Tumor, Mullerian/diagnosis , Hysterectomy , Metrorrhagia/etiology , Uterine Neoplasms/etiology , Postmenopause , Mixed Tumor, Mullerian/etiology
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